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E7 proteins from oncogenic human papillomavirus types transactivate p73: role in cervical intraepithelial neoplasia

In common with other E2F1 responsive genes such as p14(ARF) and B-myb, the promoter of p73 is shown to be positively regulated in cell lines and primary human keratinocytes by E7 proteins from oncogenic human papillomavirus (HPV) types 16, 18, 31 and 33, but not HPV 6. Mutational analysis revealed t...

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Detalhes bibliográficos
Main Authors: Brooks, L A, Sullivan, A, O'Nions, J, Bell, A, Dunne, B, Tidy, J A, Evans, D J, Osin, P, Vousden, K H, Gusterson, B, Farrell, P J, Storey, A, Gasco, M, Sakai, T, Crook, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375198/
https://ncbi.nlm.nih.gov/pubmed/11870517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600033
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