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Nucleolar damage correlates with neurotoxicity induced by different platinum drugs

Platinum-based drugs are very useful in cancer therapy but are associated with neurotoxicity in the clinic. To investigate the mechanism of neurotoxicity, dorsal root ganglia of rats treated with various platinum drugs were studied. Cell body, nuclear and nucleolar dimensions of dorsal root ganglia...

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Bibliografiske detaljer
Main Authors: McKeage, M J, Hsu, T, Screnci, D, Haddad, G, Baguley, B C
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375155/
https://ncbi.nlm.nih.gov/pubmed/11710838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2024
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