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Targeted Deficiency of the Transcriptional Activator Hnf1α Alters Subnuclear Positioning of Its Genomic Targets

DNA binding transcriptional activators play a central role in gene-selective regulation. In part, this is mediated by targeting local covalent modifications of histone tails. Transcriptional regulation has also been associated with the positioning of genes within the nucleus. We have now examined th...

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Autors principals: Luco, Reini F., Maestro, Miguel A., Sadoni, Nicolas, Zink, Daniele, Ferrer, Jorge
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375116/
https://ncbi.nlm.nih.gov/pubmed/18497863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000079
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