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PDEPT: polymer-directed enzyme prodrug therapy
Polymer-directed enzyme prodrug therapy (PDEPT) is a novel two-step antitumour approach using a combination of a polymeric prodrug and polymer-enzyme conjugate to generate cytotoxic drug selectively at the tumour site. In this study the polymeric prodrug N-(2-hydroxypropyl) methacrylamide (HPMA) cop...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375098/ https://ncbi.nlm.nih.gov/pubmed/11592781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2026 |
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