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InSite: a computational method for identifying protein-protein interaction binding sites on a proteome-wide scale

We propose InSite, a computational method that integrates high-throughput protein and sequence data to infer the specific binding regions of interacting protein pairs. We compared our predictions with binding sites in Protein Data Bank and found significantly more binding events occur at sites we pr...

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Detalhes bibliográficos
Main Authors: Wang, Haidong, Segal, Eran, Ben-Hur, Asa, Li, Qian-Ru, Vidal, Marc, Koller, Daphne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375030/
https://ncbi.nlm.nih.gov/pubmed/17868464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-9-r192
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