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Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns

BACKGROUND: Despite some degeneracy of sequence signals that govern splicing of eukaryotic pre-mRNAs, it is an accepted rule that U2-dependent introns exhibit the 3' terminal dinucleotide AG. Intrigued by anecdotal evidence for functional non-AG 3' splice sites, we carried out a human geno...

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書誌詳細
主要な著者: Szafranski, Karol, Schindler, Stefanie, Taudien, Stefan, Hiller, Michael, Huse, Klaus, Jahn, Niels, Schreiber, Stefan, Backofen, Rolf, Platzer, Matthias
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374985/
https://ncbi.nlm.nih.gov/pubmed/17672918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-8-r154
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