Expression of topoisomerase III α in normal and neoplastic tissues determined by immunohistochemistry using novel monoclonal antibody

Topoisomerases are nuclear enzymes that modulate the topological structure of DNA in order to facilitate cellular events such as replication and transcription. These enzymes are also the cellular targets of certain classes of chemotherapeutic agents termed topoisomerase poisons. A new human topoisom...

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Bibliographic Details
Main Authors: Lodge, A J, Anderson, J J, Ng, S W, Fenwick, F, Steward, M, Haugk, B, Horne, C H W, Angus, B
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2000
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374664/
https://ncbi.nlm.nih.gov/pubmed/10945498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1293
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