Topoisomerase IIα and IIß expression in childhood acute lymphoblastic leukaemia: relation to prognostic factors and clinical outcome

Background/Aims—Many regimens used in the treatment of childhood acute lymphoblastic leukaemia (ALL) include Daunorubicin or Etoposide, which act as topoisomerase poisons. It has been suggested that there may be a relation between topoisomerase expression and response to topoisomerase poisons, based...

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Detalhes bibliográficos
Main Authors: Lodge, A, Hall, A, Reid, M, McIntosh, G, Steward, M, Anderson, J, Horne, C, Angus, B
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1731267/
https://ncbi.nlm.nih.gov/pubmed/11271785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.54.1.31
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