Prognostic factors for tumour response, progression-free survival and toxicity in metastatic colorectal cancer patients given irinotecan (CPT-11) as second-line chemotherapy after 5FU failure

Our purpose was to determine, in patients with metastatic colorectal carcinoma treated with irinotecan single-agent after 5-FU failure, the most significant predictive parameters for tumour response, progression-free survival and toxicity. Between October 1992 and April 1995, 455 patients with 5-FU...

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Detalhes bibliográficos
Main Authors: Freyer, G, Rougier, P, Bugat, R, Droz, J-P, Marty, M, Bleiberg, H, Mignard, D, Awad, L, Herait, P, Culine, S, Trillet-Lenoir, V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374663/
https://ncbi.nlm.nih.gov/pubmed/10945486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1303
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