A phase II experience with neoadjuvant irinotecan (CPT-11), 5-fluorouracil (5-FU) and leucovorin (LV) for colorectal liver metastases

BACKGROUND: Chemotherapy may improve survival in patients undergoing resection of colorectal liver metastases (CLM). Neoadjuvant chemotherapy may help identify patients with occult extrahepatic disease (averting unnecessary metastasectomy), and it provides in vivo chemosensitivity data. METHODS: A p...

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Detalhes bibliográficos
Main Authors: Bathe, Oliver F, Ernst, Scott, Sutherland, Francis R, Dixon, Elijah, Butts, Charles, Bigam, David, Holland, David, Porter, Geoffrey A, Koppel, Jennifer, Dowden, Scot
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693527/
https://ncbi.nlm.nih.gov/pubmed/19457245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-156
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