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Anti-GnRH antibodies can induce castrate levels of testosterone in patients with advanced prostate cancer

D17DT consists of the GnRH decapeptide linked to diphtheria toxoid. The aim of this pilot study was to assess the tolerance of D17DT and the production of anti-GnRH antibodies from two doses, 30 and 100 μg, in patients with locally advanced prostate cancer. Twelve patients with histologically proven...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Simms, M S, Scholfield, D P, Jacobs, E, Michaeli, D, Broome, P, Humphreys, J E, Bishop, M C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374644/
https://ncbi.nlm.nih.gov/pubmed/10945488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1315
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