Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

The multidrug resistance proteins MRP1 and MRP2 are members of the same subfamily of ATP-binding cassette transporters. Besides organic molecules conjugated to negatively charged ligands, these proteins also transport cytotoxic drugs for which no negatively charged conjugates are known to exist. In...

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Detalhes bibliográficos
Main Authors: Evers, R, Haas, M de, Sparidans, R, Beijnen, J, Wielinga, P R, Lankelma, J, Borst, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374564/
https://ncbi.nlm.nih.gov/pubmed/10917554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1262
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