Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

The multidrug resistance proteins MRP1 and MRP2 are members of the same subfamily of ATP-binding cassette transporters. Besides organic molecules conjugated to negatively charged ligands, these proteins also transport cytotoxic drugs for which no negatively charged conjugates are known to exist. In...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Evers, R, Haas, M de, Sparidans, R, Beijnen, J, Wielinga, P R, Lankelma, J, Borst, P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2000
Aiheet:
Regular Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374564/
https://ncbi.nlm.nih.gov/pubmed/10917554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1262
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