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The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

Prostaglandins are involved in a wide variety of physiological and pathophysiological processes, but the mechanism of prostaglandin release from cells is not completely understood. Although poorly membrane permeable, prostaglandins are believed to exit cells by passive diffusion. We have investigate...

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Hlavní autoři: Reid, Glen, Wielinga, Peter, Zelcer, Noam, van der Heijden, Ingrid, Kuil, Annemieke, de Haas, Marcel, Wijnholds, Jan, Borst, Piet
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC170903/
https://ncbi.nlm.nih.gov/pubmed/12835412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1033060100
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