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The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

Prostaglandins are involved in a wide variety of physiological and pathophysiological processes, but the mechanism of prostaglandin release from cells is not completely understood. Although poorly membrane permeable, prostaglandins are believed to exit cells by passive diffusion. We have investigate...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Reid, Glen, Wielinga, Peter, Zelcer, Noam, van der Heijden, Ingrid, Kuil, Annemieke, de Haas, Marcel, Wijnholds, Jan, Borst, Piet
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC170903/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12835412/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1033060100
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