Altered MRP is associated with multidrug resistance and reduced drug accumulation in human SW-1573 cells.

We have analysed the contribution of several parameters, e.g. drug accumulation, MDR1 P-glycoprotein (P-gp), multidrug resistance-associated protein (MRP) and topoisomerase (topo) II, to drug resistance in a large set of drug-resistant variants of the human non-small-cell lung cancer cell line SW-15...

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Main Authors: Eijdems, E. W., Zaman, G. J., de Haas, M., Versantvoort, C. H., Flens, M. J., Scheper, R. J., Kamst, E., Borst, P., Baas, F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033977/
https://ncbi.nlm.nih.gov/pubmed/7640209
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