Φορτώνει......
Mitoxantrone and ametantrone induce interstrand cross-links in DNA of tumour cells
We show here that mitoxantrone and ametantrone induce interstrand DNA cross-links in HeLa S(3)cells. These cross-links were observed only in cellular system suggesting that metabolism of the drugs is a necessary step leading to DNA cross-linking. Biologically inactive analogue of mitoxantrone, compo...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2000
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374491/ https://ncbi.nlm.nih.gov/pubmed/10755405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1095 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|