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DNA Interstrand Cross-Linking by Epichlorohydrin
Epichlorohydrin (ECH), an important industrial chemical, is a bifunctional alkylating agent with the potential to form DNA cross-links. Occupational exposure to this suspect carcinogen leads to chromosomal aberrations, and ECH has been shown previously to undergo reaction with DNA in vivo and in vit...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2727797/ https://ncbi.nlm.nih.gov/pubmed/17441735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx700066h |
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