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Molecular analysis of the BRCA1 and BRCA2 genes in 32 breast and/or ovarian cancer Spanish families

It is estimated that about 5–10% of breast cancer cases may be due to inherited predisposition. Until now, two main susceptibility genes have been identified: BRCA1 and BRCA2. The first linkage and mutational studies suggested that mutations in these two genes would account for the majority of high-...

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Bibliografiske detaljer
Main Authors: Osorio, A, Barroso, A, Martínez, B, Cebrián, A, Román, J M San, Lobo, F, Robledo, M, Benítez, J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374482/
https://ncbi.nlm.nih.gov/pubmed/10755399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1089
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