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Screening for BRCA2 mutations in 81 Dutch breast–ovarian cancer families
We have analysed 81 families with a history of breast and/or ovarian cancer for the presence of germline mutations in BRCA2 with a number of different mutation screening techniques. The protein truncation test (PTT) for exons 10 and 11 detected four different frame-shifting mutations in six of these...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2000
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363204/ https://ncbi.nlm.nih.gov/pubmed/10638982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0892 |
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