Characteristics of small breast and/or ovarian cancer families with germline mutations in BRCA1 and BRCA2

For families with a small number of cases of breast and/or ovarian cancer, limited data are available to predict the likelihood of genetic predisposition due to mutations in BRCA1 or BRCA2. In 104 families with three or more affected individuals (average 3.8) seeking counselling at family cancer cli...

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Detalhes bibliográficos
Main Authors: Ligtenberg, M J L, Hogervorst, F B L, Willems, H W, Arts, P J W, Brink, G, Hageman, S, Bosgoed, E A J, Looij, E Van der, Rookus, M A, Devilee, P, Vos, E M A W, Wigbout, G, Struycken, P M, Menko, F H, Rutgers, E J Th, Hoefsloot, E H, Mariman, E C M, Brunner, H G, Veer, L J Van't
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362698/
https://ncbi.nlm.nih.gov/pubmed/10188893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690235
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