DNA methylation analysis at distal and proximal promoter regions of the oestrogen receptor gene in breast cancers

Oestrogen receptor α (ER-α) gene has two specific promoters, distal (P0) and proximal (P1), which induce almost identical transcripts in size due to different splicing. We examined the methylation at both promoter regions of the ER-α gene using HpaII, a methylation-sensitive restriction enzyme, prio...

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Detalhes bibliográficos
Main Authors: Iwase, H, Omoto, Y, Iwata, H, Toyama, T, Hara, Y, Ando, Y, Ito, Y, Fujii, Y, Kobayashi, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374276/
https://ncbi.nlm.nih.gov/pubmed/10471050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690631
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