DNA methylation analysis at distal and proximal promoter regions of the oestrogen receptor gene in breast cancers

Oestrogen receptor α (ER-α) gene has two specific promoters, distal (P0) and proximal (P1), which induce almost identical transcripts in size due to different splicing. We examined the methylation at both promoter regions of the ER-α gene using HpaII, a methylation-sensitive restriction enzyme, prio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Iwase, H, Omoto, Y, Iwata, H, Toyama, T, Hara, Y, Ando, Y, Ito, Y, Fujii, Y, Kobayashi, S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 1999
Pynciau:
Regular Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374276/
https://ncbi.nlm.nih.gov/pubmed/10471050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690631
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