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Effect of the N1 residue on the stability of the α-helix for all 20 amino acids

N1 is the first residue in an α-helix. We have measured the contribution of all 20 amino acids to the stability of a small helical peptide CH(3)CO-XAAAAQAAAAQAAGY-NH(2) at the N1 position. By substituting every residue into the N1 position, we were able to investigate the stabilizing role of each am...

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Autors principals: Cochran, Duncan A.E., Penel, Simon, Doig, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374126/
https://ncbi.nlm.nih.gov/pubmed/11344315
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