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Effect of the N2 residue on the stability of the α-helix for all 20 amino acids

N2 is the second position in the α-helix. All 20 amino acids were placed in the N2 position of a synthetic helical peptide (CH(3)CO-[AXAAAAKAAAAKAAGY]-NH(2)) and the helix content was measured by circular dichroism spectroscopy at 273K. The dependence of peptide helicity on N2 residue identity has b...

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Autori principali: Cochran, Duncan A.E., Doig, Andrew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374121/
https://ncbi.nlm.nih.gov/pubmed/11420432
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