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A general method for the quantitative analysis of functional chimeras: Applications from site-directed mutagenesis and macromolecular association

Two new parameters, I and C, are introduced for the quantitative evaluation of functional chimeras: I (impact) and C (context dependence) are the free energy difference and sum, respectively, of the effects on a given property measured in forward and retro chimeras. The forward chimera is made by su...

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Detalhes bibliográficos
Main Authors: Luong, Tinh N., Kirsch, Jack F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374123/
https://ncbi.nlm.nih.gov/pubmed/11344326
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