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NANOPARTICLE DELIVERED BIOSENSOR FOR REACTIVE OXYGEN SPECIES IN DIABETES

The cell’s own antioxidant response element (ARE) can be used to evaluate the complications of diabetes mellitus. The hypothesis that a synthetic ARE could be used as a genetic switch, or biosensor, to turn on and off therapeutic genes is tested herein. Mitochondrial oxidative stress (MOS) has been...

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Bibliografiske detaljer
Main Authors: Prow, Tarl W., Bhutto, Imran, Grebe, Rhonda, Uno, Koichi, Merges, Carol, Mcleod, D. Scott, Lutty, Gerard A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373906/
https://ncbi.nlm.nih.gov/pubmed/18252237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.visres.2007.09.019
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