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Role of Nrf2 in retinal vascular development and the vaso-obliterative phase of oxygen-induced retinopathy

In the initial stage of retinopathy of prematurity (ROP), hyperoxia causes retinal blood vessel obliteration. This is thought to occur in part through oxidative stress-induced apoptosis of endothelial cells. This study was designed to determine what role NF-E2-related factor 2 (Nrf2) plays in this p...

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Détails bibliographiques
Publié dans:Exp Eye Res
Auteurs principaux: Uno, Koichi, Prow, Tarl W., Bhutto, Imran A., Yerrapureddy, Adi, McLeod, D. Scott, Yamamoto, Masayuki, Reddy, Sekhar P., Lutty, Gerard A.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917303/
https://ncbi.nlm.nih.gov/pubmed/20064509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2009.12.012
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