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Ocular Nanoparticle Toxicity and Transfection of the Retina and Retinal Pigment Epithelium

Chitosan (CHI), PCEP (poly{[(cholesteryl oxocarbonylamido ethyl) methyl bis(ethylene) ammonium iodide] ethyl phosphate}), and magnetic (MNP) nanoparticles were evaluated for the safe delivery of genes in the eye. Rabbits were injected with nanoparticles either intra-vitreally (IV) or sub-retinally (...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Prow, Tarl W., Bhutto, Imran, Kim, Sahng Y., Grebe, Rhonda, Merges, Carol, McLeod, D. Scott, Uno, Koichi, Mennon, Mohamed, Rodriguez, Li, Leong, Kam, Lutty, Gerard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818568/
https://ncbi.nlm.nih.gov/pubmed/18640079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2008.06.003
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