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Integrin α6β4 Promotes Migration, Invasion through Tiam1 Upregulation, and Subsequent Rac Activation

The lethality of pancreatic adenocarcinoma stems from an elevated incidence of tumor cell invasion and metastasis that are mediated by mechanisms not yet understood. Recent studies indicate that the proinvasive integrin α6β4 is highly upregulated in pancreatic adenocarcinomas. To assess the importan...

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Detalhes bibliográficos
Main Authors: Cruz-Monserrate, Zobeida, O'Connor, Kathleen L
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373869/
https://ncbi.nlm.nih.gov/pubmed/18472958
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