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Conformational transition states of a β-hairpin peptide between the ordered and disordered conformations in explicit water

The conformational transition states of a β-hairpin peptide in explicit water were identified from the free energy landscapes obtained from the multicanonical ensemble, using an enhanced conformational sampling calculation. The β-hairpin conformations were significant at 300 K in the landscape, and...

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Bibliographic Details
Main Authors: Kamiya, Narutoshi, Higo, Junichi, Nakamura, Haruki
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373694/
https://ncbi.nlm.nih.gov/pubmed/12237452
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