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Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase

Crystal structures have been determined for free Escherichia coli hypoxanthine phosphoribosyltransferase (HPRT) (2.9 Å resolution) and for the enzyme in complex with the reaction products, inosine 5`-monophosphate (IMP) and guanosine 5`-monophosphate (GMP) (2.8 Å resolution). Of the known 6-oxopurin...

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Detalhes bibliográficos
Main Authors: Guddat, Luke W., Vos, Siska, Martin, Jennifer L., Keough, Dianne T., de Jersey, John
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373649/
https://ncbi.nlm.nih.gov/pubmed/12070315
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