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TEM-1 β-lactamase as a scaffold for protein recognition and assay

A large number of different proteins or protein domains have been investigated as possible scaffolds to engineer antibody-like molecules. We have previously shown that the TEM-1 β-lactamase can accommodate insertions of random sequences in two loops surrounding its active site without compromising i...

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Detalhes bibliográficos
Main Authors: Legendre, Daniel, Vucic, Bénédicte, Hougardy, Vincent, Girboux, Anne-Lise, Henrioul, Christophe, Van Haute, Julien, Soumillion, Patrice, Fastrez, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373628/
https://ncbi.nlm.nih.gov/pubmed/12021449
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