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Active TEM-1 β-lactamase mutants with random peptides inserted in three contiguous surface loops
Engineering of alternative binding sites on the surface of an enzyme while preserving the enzymatic activity would offer new opportunities for controlling the activity by binding of non-natural ligands. Loops and turns are the natural substructures in which binding sites might be engineered with thi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242396/ https://ncbi.nlm.nih.gov/pubmed/16963643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062303606 |
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