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Functional control of the binuclear metal site in the metallo-β-lactamase-like fold by subtle amino acid replacements

At present there are three protein families that share a common structural domain, the αβ/βα fold of class B β-lactamases: zinc β-lactamases, glyoxalases II, and A-type flavoproteins. A detailed inspection of their superimposed structures was undertaken and showed that although these proteins contai...

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Autori principali: Gomes, Cláudio M., Frazão, Carlos, Xavier, António V., Legall, Jean, Teixeira, Miguel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373467/
https://ncbi.nlm.nih.gov/pubmed/11847294
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