NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA

Nonsense-mediated messenger RNA decay (NMD) generally degrades mRNAs that prematurely terminate translation as a means of quality control. NMD in mammalian cells targets newly spliced mRNA that is bound by the cap-binding protein heterodimer CBP80/20 and one or more post-splicing exon junction compl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Woeller, Collynn F, Gaspari, Martina, Isken, Olaf, Maquat, Lynne E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2008
Schlagworte:
Scientific Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373368/
https://ncbi.nlm.nih.gov/pubmed/18369367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.36
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