Llwytho...

SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs

UPF1 functions in both Staufen 1 (STAU1)-mediated mRNA decay (SMD) and nonsense-mediated mRNA decay (NMD), which we show here are competitive pathways. STAU1- and UPF2-binding sites within UPF1 overlap so that STAU1 and UPF2 binding to UPF1 appear to be mutually exclusive. Furthermore, down-regulati...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gong, Chenguang, Kim, Yoon Ki, Woeller, Collynn F., Tang, Yalan, Maquat, Lynne E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632170/
https://ncbi.nlm.nih.gov/pubmed/19095803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1717309
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