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Single-molecule nonequilibrium periodic Mg(2+)-concentration jump experiments reveal details of the early folding pathways of a large RNA
The evolution of RNA conformation with Mg(2+) concentration ([Mg(2+)]) is typically determined from equilibrium titration measurements or nonequilibrium single [Mg(2+)]-jump measurements. We study the folding of single RNA molecules in response to a series of periodic [Mg(2+)] jumps. The 260-residue...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2373323/ https://ncbi.nlm.nih.gov/pubmed/18448679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801436105 |
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