Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice

Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that plays an important role in integrin-mediated signal transduction. To explore the role and mechanisms of FAK in cardiac development, we inactivated FAK in embryonic cardiomyocytes by crossing the floxed FAK mice with myosin light chain...

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Bibliografiska uppgifter
Huvudupphovsmän: Peng, Xu, Wu, Xiaoyang, Druso, Joseph E., Wei, Huijun, Park, Ann Yong-Jin, Kraus, Marc S., Alcaraz, Ana, Chen, Ju, Chien, Shu, Cerione, Richard A., Guan, Jun-Lin
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2008
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373317/
https://ncbi.nlm.nih.gov/pubmed/18448675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802319105
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