Evidence that hepatocyte turnover is required for rapid clearance of duck hepatitis B virus during antiviral therapy of chronically infected ducks.

Duck hepatitis B virus (DHBV) DNA synthesis in congenitally infected ducks is inhibited by 2'-deoxycarbocyclic guanosine (2'-CDG). Three months of therapy reduces the number of infected hepatocytes at least 10-fold (W.S. Mason, J. Cullen, J. Saputelli, T.-T. Wu, C. Liu, W.T. London, E. Lus...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Fourel, I, Cullen, J M, Saputelli, J, Aldrich, C E, Schaffer, P, Averett, D R, Pugh, J, Mason, W S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237301/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966625/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.8321-8330.1994
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