Human anti-V2 monoclonal antibody that neutralizes primary but not laboratory isolates of human immunodeficiency virus type 1.

A human immunoglobulin G1 lambda monoclonal antibody (MAb), 697-D, was developed that recognizes the V2 region of human immunodeficiency virus type 1 (HIV-1) gp120. Substitutions at amino acid positions 176/177, 179/180, 183/184, and 192 to 194 in the V2 loop of gp120 each completely abolished the b...

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Autores principales: Gorny, M K, Moore, J P, Conley, A J, Karwowska, S, Sodroski, J, Williams, C, Burda, S, Boots, L J, Zolla-Pazner, S
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC237300/
https://ncbi.nlm.nih.gov/pubmed/7525987
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