Human anti-V2 monoclonal antibody that neutralizes primary but not laboratory isolates of human immunodeficiency virus type 1.

A human immunoglobulin G1 lambda monoclonal antibody (MAb), 697-D, was developed that recognizes the V2 region of human immunodeficiency virus type 1 (HIV-1) gp120. Substitutions at amino acid positions 176/177, 179/180, 183/184, and 192 to 194 in the V2 loop of gp120 each completely abolished the b...

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Vydáno v:	J Virol
Hlavní autoři:	Gorny, M K, Moore, J P, Conley, A J, Karwowska, S, Sodroski, J, Williams, C, Burda, S, Boots, L J, Zolla-Pazner, S
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7525987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.8312-8320.1994
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