A late adenovirus factor induces eIF-4E dephosphorylation and inhibition of cell protein synthesis.

Adenovirus prevents host cell protein synthesis during its late phase of replication in large part by causing the underphosphorylation of translation initiation factor eIF-4E, a component of initiation factor eIF-4F (cap-binding protein complex). Late adenovirus mRNAs are preferentially translated b...

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Bibliographic Details
Main Authors: Zhang, Y, Feigenblum, D, Schneider, R J
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC237141/
https://ncbi.nlm.nih.gov/pubmed/7933086
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