Structural Basis for Competitive Inhibition of eIF4G-Mnk1 Interaction by the Adenovirus 100-Kilodalton Protein

Translation of most cellular mRNAs involves cap binding by the translation initiation complex. Among this complex of proteins are cap-binding protein eIF4E and the eIF4E kinase Mnk1. Cap-dependent mRNA translation generally correlates with Mnk1 phosphorylation of eIF4E when both are bound to eIF4G....

Full description

Saved in:
Bibliographic Details
Published in:J Virol
Main Authors: Cuesta, Rafael, Xi, Qiaoran, Schneider, Robert J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434077/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15220445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.14.7707-7716.2004
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items