Cell cycle-dependent colocalization of BARD1 and BRCA1 proteins in discrete nuclear domains

Germ-line mutations of the BRCA1 gene predispose women to early-onset breast and ovarian cancer by compromising the gene’s presumptive function as a tumor suppressor. Although the biochemical properties of BRCA1 polypeptides are not understood, their expression pattern and subcellular localization s...

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Dettagli Bibliografici
Autori principali: Jin, Ying, Xu, Xie L., Yang, Meng-Chun W., Wei, Fanglin, Ayi, Teck-Choon, Bowcock, Anne M., Baer, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC23707/
https://ncbi.nlm.nih.gov/pubmed/9342365
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