The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding.

The integrase protein of human immunodeficiency virus type 1 removes two nucleotides from the 3' ends of reverse-transcribed human immunodeficiency virus type 1 DNA (3' processing) and covalently inserts the processed ends into a target DNA (DNA strand transfer). Mutant integrase proteins...

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Vydáno v:J Virol
Hlavní autoři: Engelman, A, Hickman, A B, Craigie, R
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1994
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236996/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8057470/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.9.5911-5917.1994
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