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The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding.

The integrase protein of human immunodeficiency virus type 1 removes two nucleotides from the 3' ends of reverse-transcribed human immunodeficiency virus type 1 DNA (3' processing) and covalently inserts the processed ends into a target DNA (DNA strand transfer). Mutant integrase proteins...

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Bibliografiska uppgifter
Huvudupphovsmän: Engelman, A, Hickman, A B, Craigie, R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC236996/
https://ncbi.nlm.nih.gov/pubmed/8057470
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