Central nervous system-derived cells express a kappa B-binding activity that enhances human immunodeficiency virus type 1 transcription in vitro and facilitates TAR-independent transactivation by Tat.

The Tat protein of human immunodeficiency virus type 1 (HIV-1) is a potent activator of long terminal repeat-directed transcription. While in most cell types, activation requires interaction of Tat with the unusual transcription element TAR, astrocytic glial cells support TAR-independent transactiva...

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Pubblicato in:	J Virol
Autori principali:	Taylor, J P, Pomerantz, R J, Raj, G V, Kashanchi, F, Brady, J N, Amini, S, Khalili, K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8189531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.6.3971-3981.1994
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