Central nervous system-derived cells express a kappa B-binding activity that enhances human immunodeficiency virus type 1 transcription in vitro and facilitates TAR-independent transactivation by Tat.

The Tat protein of human immunodeficiency virus type 1 (HIV-1) is a potent activator of long terminal repeat-directed transcription. While in most cell types, activation requires interaction of Tat with the unusual transcription element TAR, astrocytic glial cells support TAR-independent transactiva...

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Detalhes bibliográficos
Main Authors: Taylor, J P, Pomerantz, R J, Raj, G V, Kashanchi, F, Brady, J N, Amini, S, Khalili, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC236903/
https://ncbi.nlm.nih.gov/pubmed/8189531
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