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TAR-independent transactivation by Tat in cells derived from the CNS: a novel mechanism of HIV-1 gene regulation.

The Tat protein of human immunodeficiency virus type 1 (HIV-1) is essential for productive infection and is a potential target for antiviral therapy. Tat, a potent activator of HIV-1 gene expression, serves to greatly increase the rate of transcription directed by the viral promoter. This induction,...

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Autors principals: Taylor, J P, Pomerantz, R, Bagasra, O, Chowdhury, M, Rappaport, J, Khalili, K, Amini, S
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC556874/
https://ncbi.nlm.nih.gov/pubmed/1505523
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