TAR-independent transactivation by Tat in cells derived from the CNS: a novel mechanism of HIV-1 gene regulation.

The Tat protein of human immunodeficiency virus type 1 (HIV-1) is essential for productive infection and is a potential target for antiviral therapy. Tat, a potent activator of HIV-1 gene expression, serves to greatly increase the rate of transcription directed by the viral promoter. This induction,...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Taylor, J P, Pomerantz, R, Bagasra, O, Chowdhury, M, Rappaport, J, Khalili, K, Amini, S
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1992
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556874/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1505523/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05418.x
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