A single amino acid change determines persistence of a chimeric Theiler's virus.
The DA strain of Theiler's virus persists in the central nervous system of mice and causes chronic inflammation and demyelination. On the other hand, the GDVII strain causes an acute encephalitis and does not persist in surviving animals. Series of recombinants between infectious cDNA clones of the...
Gardado en:
| Publicado en: | J Virol |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1994
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236827/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7512164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.3364-3368.1994 |
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